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One of the anime projects to commemorate the 20th anniversary of the Precure franchise, this sequel will show Nozomi Yumehara and other characters from Yes! Precure 5 GoGo! and Precure Splash Star as grown-ups.

A girl named Haru Asagi works as a maid for the Miyanomori family, which is headed by one of Japan's most powerful magnates. However, the family head suddenly announces that he is retiring, so one of his six sons must assume control of the family.

Natsume Takashi has the ability to see spirits, which he has long kept secret. However, once he inherits a strange book that belonged to his deceased grandmother, Reiko, he discovers the reason why spirits surround him.

During the summer festival five years ago, two girls met at a mysterious tree and saw two glowing spheres. Now, these two girls--Saki Hyuga, ace pitcher on the school softball team; and Mai Mishou, who prefers sketching over stargazing--are chosen by the spirits of flowers (Flappy) and birds (Choppy) to restore the Seven Fountains and save their worlds from Dark Autumn. Together, they are the NEW Pretty Cure.

Nanami Takahashi is a high school student entering her first year. Immediately on her first day however, she becomes the victim of a practical joke by the school's most popular guy, Motoharu Yano, who coincidentally also ends up in her class. While the two get off to a rocky start, they soon find themselves falling in love with one another and begin dating. But their relationship is marred by Yano's past which includes the death of Yano's previous girlfriend, Nana Yamamoto, and the betrayal surrounding her death. To make matters more complicated her younger sister, Yuri, is in the same class as Yano and Nanami. As Yano struggles to come to grips with Nana's death and his unresolved feelings for her, so too must Nanami learn to understand Yano if the two hope to continue their relationship with one another.

The plot of the series revolves around three youkai, Bem, Bera and Barro, who arrive at a large coastal city and come across an evil atmosphere, which was brought about by immoral behavior by humans and mischief caused by monsters and youkai. They therefore decide to stay in the city, fighting against other monsters and yōkai which attack humans, making a few friends in the way. Even though the three youkai are often abused by other human beings due to their appearance, they still strive in protecting the human populace of the city from other monsters, one day hoping to become human beings in return for their good actions.

Keiichi Morisato is looking forward to university life. But in reality, he has no luck in anything, and he has trouble with clubs, love, etc. The truth is that he has an unlucky star above his head. One day, Keiichi is stuck watching the dorm while his sempai are away, and has a mountain of chores to do to boot. But Keiichi is a good-natured person, and is set about doing his duties. As he is about to finish his final chore, he makes a phone call to his sempai. But the words that came through the receiver are, 'Goddess Help Line.' Shortly afterwards, a beautiful goddess named Belldandy appears in front of him from the mirror of his room.

Kenzou Tenma, a Japanese brain surgeon in Germany, finds his life in utter turmoil after getting involved with a psychopath that was once a former patient.

Loki, the Norse god of mischief, has been exiled to the human world for what was apparently was a bad joke. Along with being exiled, he’s forced to take the form of a child. He’s told the only way he can get back to the world of the gods is if he can collect auras of evil that take over human hearts, and so to do this he runs a detective agency. Loki is soon joined by a human girl named Mayura who is a maniac for mysteries, and she soon helps out in her own way. However, soon other Norse gods begin to appear, and most have the intent to assassinate Loki for reasons unclear.

The Social Welfare Agency saves the lives of terminal patients using cybernetic implants. Then it teaches them to kill. After surviving the slaughter of her family, young Henrietta awakens to her new life at the Agency with a rebuilt body and no memory. Teamed with Jose, who is responsible for turning her into the perfect assassin, Henrietta’s been given a second chance—but at what cost?
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